A new stem cell therapy for Type 1 diabetes has received the “green light” from the FDA and Health Canada, signaling the start of clinical trials to assess the safety and efficacy of the technique. The therapy is being developed by ViaCyte, a California-based company focused on regenerative medicine, and it focuses on implanting healthy, functioning pancreatic cells – islet cells – grown from stem cells. The clinical trial will be the first ever to evaluate stem cell-derived islet cells to treat Type 1 diabetes. ViaCyte’s Novel Approach In Type 1 diabetes, insulin-producing islet cells in the pancreas are destroyed…
The number of bacteria showing marked resistance to antibiotic therapy in patients with diabetic foot ulcers is on the rise, according to the results of a recent study conducted by researchers in Peru. The study results were presented this spring at the ENDO 2017 conference in Florida. In their study, the researchers isolated bacteria from 88 patients with diabetic foot ulcers who were treated with early ambulatory surgical debridement from 2010 to 2014, identifying the types of bacteria present in the ulcers as well as evaluating the germs’ responses to treatment with antibiotics. Cultures were removed from the base of the ulcer following the debridement procedure.…
Stem cells have been making headlines in recent years for their unique role in regenerating damaged tissue and even growing completely new tissue and organs. Now, researchers from Tufts University School of Dental Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts say they’ve found a way to use wound tissue from diabetic foot ulcers to grow new tissues that could aid in healing those ulcers. Diabetic foot ulcers are a very serious complication of diabetes, and their healing is hampered by the circulatory and nerve damage that occurs as a result of the disease. Because they take a long time to heal, ulcers…
About 2.4 million people with diabetes will also develop a foot ulcer, a very serious sore that can result in widespread infection and even amputation. While normally, a sore will heal relatively quickly and the body’s immune system will ward off infection, in diabetes, the healing and immune systems can be compromised, which makes the development of a serious infection far more likely. Low-Cost Interventions Are Very Effective Because multiple factors cause and contribute to the development and increasing severity of foot ulcers, it is no surprise that managing these ulcers is very costly. Rigorous prevention strategies are of course, the best…
“Smart” Technology Offers Promise for Prevention of Diabetic Foot Ulcers An ounce of prevention is worth a pound of cure, and nowhere does that saying ring truer than in patients with diabetic foot ulcers. These dangerous and slow-to-heal sores are a common cause of serious infections and foot and limb amputations among people with diabetes, and while treatment options have certainly improved and evolved during the past decade, preventing ulcers from forming is still the best way to avoid devastating complications. Now a new study from researchers at Baylor College of Medicine and the University of Arizona finds “smart” technology,…