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Peptide Therapy Shows Promise for Patients Newly Diagnosed With Type 1 Diabetes


By: Tags: type 1 diabetes
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A new type of immunotherapy promises hope for people newly diagnosed with type 1 diabetes, according to a study conducted by researchers from Cardiff University School of Medicine in the United Kingdom. The study and its results were recently published in Science Translational Medicine, and focused on patients who were injected with the immunotherapy agent called human leukocyte antigen-DR4 (DRB1*0401)-restricted immunodominant proinsulin peptide. Unlike type 2 diabetes, which is a metabolic disorder typically triggered by insulin resistance and obesity, type 1 diabetes is caused by an aberrant immune system response that results in damage and destruction of beta cells (Ꞵ cells or islet cells), special pancreatic…


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Blood-Derived Stem Cells Hold Promise for Diabetes Treatment  


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In recent years, stem cells have presented several exciting possibilities for the treatment of an array of diseases and medical conditions, and now, a new study published in Stem Cells Translational Medicine reports the cells may be helpful in developing treatments for patients with type 1 diabetes. Improving Insulin Production In type 1 diabetes, the body’s immune system attacks and destroys beta cells (sometimes called islet cells), special cells in the pancreas that are responsible for producing the hormone insulin. When cells are destroyed, the pancreas can’t produce the amount of insulin the body needs to control blood sugar (or glucose). Over…


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How 3D Printing Is Shaping the Future of Diabetic Foot Care  


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For years, digitized foot measurements and “maps” have enabled orthopedic shoemakers to make customized shoe insoles for those who suffer from diabetes. And now, German researchers are taking digitization one step further, tying in digital foot-mapping with 3D printing technology to produce insoles that are even more accurate – and much less costly to produce. Named LAUF, a German acronym for “laser-assisted construction of customized footwear,” the technology initiative is being pioneered by Germany’s Federal Ministry of Education and Research and researchers from the Fraunhofer Institutes for Mechanics of Materials IWM. Researchers from these agencies are joining with industry partners to refine…


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Diabetic Foot Care

Stem Cell Therapy Holds New Promise for Type 1 Diabetics


By: Tags: Diabetic Foot Care in Los Angeles stem cell therapy
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A new stem cell therapy for Type 1 diabetes has received the “green light” from the FDA and Health Canada, signaling the start of clinical trials to assess the safety and efficacy of the technique. The therapy is being developed by ViaCyte, a California-based company focused on regenerative medicine, and it focuses on implanting healthy, functioning pancreatic cells – islet cells – grown from stem cells. The clinical trial will be the first ever to evaluate stem cell-derived islet cells to treat Type 1 diabetes. ViaCyte’s Novel Approach In Type 1 diabetes, insulin-producing islet cells in the pancreas are destroyed…


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Antibiotic Resistance Poses Challenges for Treatment of Diabetic Foot Ulcers


By: Tags: ambulatory surgical debridement Diabetic Foot Care in Los Angeles Diabetic Foot Ulcers
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The number of bacteria showing marked resistance to antibiotic therapy in patients with diabetic foot ulcers is on the rise, according to the results of a recent study conducted by researchers in Peru. The study results were presented this spring at the ENDO 2017 conference in Florida. In their study, the researchers isolated bacteria from 88 patients with diabetic foot ulcers who were treated with early ambulatory surgical debridement from 2010 to 2014, identifying the types of bacteria present in the ulcers as well as evaluating the germs’ responses to treatment with antibiotics. Cultures were removed from the base of the ulcer following the debridement procedure.…


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